Hailong Yan group publishes on Angewandte Chemie International Edition

Time：2022-02-16

add：Posted by Yangfeng Li

???? On Feb. 16th, 2022, Professor Hailong Yan's group at the School of Pharmaceutical Science of Chongqing University has published an article on Angewandte Chemie International Edition entitled "An Isolable Vinylidene ortho-Quinone Methide: Synthesis, Structure and Reactivity".? ? ?Commonly, an elusive intermediate is generated from a precursor and then trapped and consumed in a reaction. Vi...

Yizhou Li group publishes on Organic Letters

Time：2022-01-24

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??? The Medicinal Chemistry Biology Group of Chongqing University has published an article in Organic Letters entitled " DNA-Compatible Diversification of Indole π-Activated Alcohols via a Direct Dehydrative Coupling Strategy".??? DNA-encoded chemical library (DEL) is a new technology that combines the diversity advantages of combinatorial chemistry with the specific encoding of DNA tags, to s...

Yizhou Li group publishes on Angewandte Chemie International Edition

Time：2022-01-08

add：Posted by Yangfeng Li

The Medicinal Chemistry Biology Group of Chongqing University has published an article in Angewandte Chemie International Edition entitled "Reversible Covalent Headpiece Enables Interconversion between Double-stranded DNA-encoded Chemical Libraries".The discovery of lead compounds is the starting point for innovative drug development, and it’s also a difficult point in drug development. DNA-en...

Weiwei Xue Group publishes on Nucleic Acids Research

Time：2021-11-03

add：Posted by Yangfeng Li

??? In a paper “SYNBIP: synthetic binding proteins for research, diagnosis and therapy” recently published in Nucleic Acids Research, researchers from the School of Pharmaceutical Sciences at Chongqing University (CQU) report a new platform of synthetic binding proteins (SBPs).? ? ???? The success of protein engineering and design has extensively expanded the protein space, which presents a p...